Publications by authors named "A Farber"
Objective: Wound, Ischemia, and foot Infection (WIfI) staging was established to provide objective classification in patients with chronic limb-threatening ischemia (CLTI) and to predict 1-year major amputation risk. Our goal was to validate WIfI staging using data from the Best Endovascular vs Best Surgical Therapy in Patients with CLTI (BEST-CLI) trial.
Methods: Data from the BEST-CLI Trial, a prospective randomized trial comparing surgical revascularization (OPEN) and endovascular revascularization (ENDO), were used to assess the association of WIfI stage on long-term outcomes in an intention-to-treat analysis.
Objective: Wound complications are one of the major sources of morbidity after open vascular procedures, especially lower extremity bypass (LEB). The preferred skin closure method is based on surgeon preference. Because no data clearly demonstrates the superiority of one method over the other, we aimed to compare outcomes of staples vs sutures for skin closure after LEB.
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- The study aimed to investigate outcomes of female patients with Critical Limb Ischemia (CLI) compared to males in the BEST-CLI trial, particularly focusing on disparities in diagnosis and treatment for peripheral artery disease.
- It analyzed male and female patients undergoing open surgical bypass or endovascular therapy, assessing outcomes like major amputation, reintervention, and all-cause death, using data from cohorts 1 and 2 of the trial.
- Results showed that females constituted only 28% of the cohort and had different clinical presentations than males, with females experiencing higher instances of rest pain and fewer adequate vein options for surgical bypass, leading to significant differences in outcomes at one year.
Objective: Several observational studies have demonstrated an association between diabetes mellitus (DM) and above-ankle amputation after lower extremity revascularization (LER). However, data from prospective randomized trials is lacking. This analysis compares the outcomes of patients with and without DM enrolled in the Best Endovascular vs Best Surgical Therapy in patients with Chronic Limb-Threatening Ischemia (BEST-CLI) trial.
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