Publications by authors named "A Faour"
Introduction: Myocardial Infarct Size (IS) determined soon after ST-segment elevation myocardial infarction (STEMI) has prognostic significance, and can be assessed by cardiac biomarker levels, electrocardiographic (ECG) parameters, and imaging modalities (including echocardiography and cardiac magnetic resonance imaging [CMRI]).
Objectives And Methods: We evaluated methods of IS assessment, 12-lead ECG Selvester QRS scores and high-sensitivity Troponin T (hsTnT) levels measured ≥48hr (plateau phase of hsTnT elevation), compared to paired CMRIs and echocardiograms, in a prospective cohort of patients with STEMI undergoing percutaneous coronary intervention (PCI) during the index hospitalisation. Associations were determined between IS, as assessed by these methods, and 24-month major adverse cardiac events (MACE), a hierarchical composite of: death, stroke and hospitalization for heart failure.
Article Synopsis
- Spinal muscular atrophy (SMA) is a rare inherited disease that varies in symptoms and requires diverse care for affected patients, prompting a systematic literature review of pharmacoeconomic evaluations for existing therapies.
- The review focused on studies published in English after 2016, analyzing 14 relevant studies for quality and reporting standards using established checklists, and highlighting the need for cost-effectiveness analysis even for high-cost treatments.
- The findings stress the importance of establishing specific willingness to pay thresholds for orphan medicines to ensure that SMA patients have access to safe and effective therapies, while also emphasizing the necessity of considering new information in medication decisions.
Aims: Pharmaco-invasive percutaneous coronary intervention (PI-PCI) is recommended for patients with ST-elevation myocardial infarction (STEMI)who are unable to undergo timely primary PCI (pPCI). The present study examined late outcomes after PI-PCI (successful reperfusion followed by scheduled PCI or failed reperfusion and rescue PCI)compared with timely and late pPCI (>120 min from first medical contact).
Methods And Results: All patients with STEMI presenting within 12 h of symptom onset, who underwent PCI during their initial hospitalization at Liverpool Hospital (Sydney), from October 2003 to March 2014, were included.
The weak potential of using the sole outdoor concentrations to represent personal exposure to PM is confirmed by the literature; therefore, it is important to account for a person's movements over time when estimating the short-term personal air pollution exposure within different microenvironments (MEs). This study is an example of applying an assessment method of the exposure to PM in different microenvironments at different temporal scales. A low-cost particle counter (the Dylos 1700) was used; its performance was validated in comparison with equivalent instruments such the SidePak AM520 Personal Aerosol Monitor (R = 0.
View Article and Find Full Text PDF