Publications by authors named "A Falorni"
Article Synopsis
- * Pasireotide, a treatment for these conditions, can cause hyperglycemia; current guidelines recommend managing this through lifestyle changes, metformin, and other medications like DPP-4 inhibitors and GLP-1 receptor agonists.
- * Recent expert consensus suggests prioritizing GLP-1 receptor agonists for hyperglycemia management in acromegaly patients and considers using SGLT2 inhibitors for those with cardiovascular or renal issues, while emphasizing the need for further studies to assess potential risks.
Background/aim: Survival rates of prostate cancer (PCa) patients have improved considerably as a result of earlier diagnosis and therapies, including radiotherapy (RT) and androgen deprivation therapy (ADT). Patients on ADT develop cancer treatment-induced bone loss (CTIBL) and a high risk of fragility fractures. Bone health (BH) assessment is strongly recommended, together with timely initiation of treatments, to counteract CTIBL and preserve bone strength.
View Article and Find Full Text PDFThe autoimmune polyglandular syndrome type 1 (APS1) is caused by pathogenic variants of the autoimmune regulator () gene, located in the chromosomal region 21q22.3. The related protein, AIRE, enhances thymic self-representation and immune self-tolerance by localization to chromatin and anchorage to multimolecular complexes involved in the initiation and post-initiation events of tissue-specific antigen-encoding gene transcription.
View Article and Find Full Text PDFObjective: Type 1 diabetes (T1D) is frequently associated with other autoimmune diseases (AIDs). Although most of T1D patients are sporadic cases (S-T1D), 10% to 15% have a familial form (F-T1D) involving 2 or more first-degree relatives. This study evaluated the effect of T1D family aggregation and age onset on AIDs occurrence.
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