Publications by authors named "A Fallon"
Background: Falls are frequently reported within the HSE. The Irish Longitudinal Study on Ageing(TILDA) found that 40% of over 50 s experience a fall in a two year period, with 20% requiring hospital attendance (1). It has been estimated that the cost of injuries related to falls in older people will increase exponentially over the coming years (2).
View Article and Find Full Text PDFOxidative stress generated as a normal byproduct of aerobic metabolism is minimized by the enzyme catalase (CAT; EC 1.11.1.
View Article and Find Full Text PDFProjected Annual Lecanemab Treatment Eligibility in an Irish Regional Specialist Memory Clinic.
Int J Geriatr Psychiatry
October 2024
Article Synopsis
- The study aims to explore patient eligibility for lecanemab therapy for Alzheimer's Disease (AD) at a Regional Specialist Memory Clinic, emphasizing the importance of timely treatment in early AD cases.
- A retrospective analysis was conducted on 188 new patients over a year, assessing their diagnostic data and biomarker status to determine eligibility based on Appropriate Use Criteria (AUC) and clinical trial standards.
- Results showed only 5.9% of the patients were eligible according to AUC, with a higher eligibility rate of 26.2% among those with biomarker positive Alzheimer's, highlighting major barriers like lack of biomarker confirmation and cognitive ineligibility.
Online Utilization of the Nominal Group Technique to Gather Consensus Opinion Across Geographically Disparate Locations.
J Contin Educ Health Prof
October 2024
Introduction: The nominal group technique (NGT) is a structured focus group that gathers opinion and generates consensus from groups on topics of interest. Previous studies using online NGTs (ONGTs) in health have been conducted in regions of high population density and internet connectivity. This activity aimed to determine the feasibility and utility of ONGTs in gathering opinion and reaching consensus on curriculum topics for a continuing research education program for health professionals dispersed across various locations in Southern Queensland.
View Article and Find Full Text PDFArticle Synopsis
- Plasma p-tau217 is identified as a promising blood-based marker for detecting Alzheimer Disease (AD) pathology, particularly in memory clinic patients undergoing lumbar punctures.
- A study involving 108 participants found that plasma p-tau217 levels were significantly higher in those with detected amyloid (Aβ) pathology compared to those without, indicating its strong potential for diagnosis.
- The analysis showed that plasma p-tau217 had excellent performance metrics for Aβ detection (AUC: 0.91), outperforming other biomarkers and suggesting it could be a reliable tool in Alzheimer's diagnostics.