Publications by authors named "A Falade"
Chimeric antigen receptor (CAR) T-cell therapy has revolutionized treatment of aggressive large B-cell lymphoma (aLBCL). Patients with transformed indolent non-Hodgkin lymphoma (tiNHL) were included in key CAR trials, but outcomes of CAR for this distinct, historically high-risk group are poorly understood. We conducted a multicenter retrospective study of 1182 patients with aLBCL receiving standard-of-care CAR T between 2017 and 2022, including 338 (29%) with tiNHL.
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- A study in Nigeria examined primary healthcare workers' knowledge and perception of mpox, noting limited research on the topic despite rising cases from 2017 to 2022.
- The survey assessed knowledge across various areas, revealing that while 78.3% were aware of mpox, understanding of its transmission was notably low, especially in Lagos compared to other regions.
- Most healthcare workers recognized that mpox could affect anyone, but nearly half felt that they couldn't protect themselves from it, highlighting gaps in knowledge and perceived vulnerability.
Exploring the feeding practices of mothers of under-five children and how household members influence exclusive breastfeeding in Jigawa State, Nigeria - A qualitative study.
Glob Public Health
January 2024
Child nutrition interventions in low-income settings are variably effective as strategies often focus on primary caregivers, with less attention given to other household members. This study explored the influence of household members on exclusive breastfeeding and the feeding practices of mothers of under-five children in Jigawa State, Northern Nigeria. As part of a cluster randomised controlled trial in Jigawa State, we conducted an ethnographic process evaluation.
View Article and Find Full Text PDFBackground: In Nigeria, COVID-19 vaccines were delivered through outreach activities, as well as integrated within routine immunisation. However, evaluations of integrated approaches for novel vaccines are scarce. We aimed to understand the perceived benefits and challenges of integrating the COVID-19 vaccine within routine immunisation in Nigeria, and identify ways to strengthen this approach.
View Article and Find Full Text PDFEffect of a participatory whole-systems approach on mortality in children younger than 5 years in Jigawa state, Nigeria (INSPIRING trial): a community-based, parallel-arm, pragmatic, cluster randomised controlled trial and concurrent mixed-methods process evaluation.
Lancet Glob Health
December 2024
Article Synopsis
- Nigeria had the highest child mortality rate globally in 2019, prompting a study to address this issue using a whole-systems approach in the Kiyawa area of Jigawa state.
- A community-based controlled trial was conducted, randomly assigning health care clusters to either an intervention or a control group, targeting mothers and children in participating households.
- The intervention included participatory learning and action groups, a partnership-defined quality scorecard, and training for healthcare workers, aiming to reduce child mortality rates over a specified period.