Publications by authors named "A Fagnani"
To assess whether expectant observation of infants ≤ 90 days old with small suprarenal masses (sSRMs) could avoid unnecessary surgery without impacting outcome. Infants ≤ 90 days with a ≤ 5 cm mass, without midline extension or lymph node or distant spread were registered (ClinicalTrials.org:NCT01728155).
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- - The study investigates how SARS-CoV-2 affects the placenta and pregnancy outcomes by analyzing tissues from both infected and non-infected pregnant women.
- - SARS-CoV-2 was found in about half of the placental tissues from infected women, but generally did not correlate with major health issues for mothers or newborns, except in one case with severe damage.
- - The research indicates that while the placenta can block vertical transmission of the virus, severe infections can still cause significant damage, potentially leading to problems for the newborn.
Purpose: Stage 4S neuroblastoma, a tumor affecting infants, is characterized by the capacity to regress spontaneously and high cure rate. About a third of these infants undergo tumor progression requiring antitumor treatment and 10-15% eventually die. In case of metastatic progression, it may occur either at 4S sites (mainly liver) or sites characterizing stage 4 (mainly bone).
View Article and Find Full Text PDFPurpose: To clarify the role of primary tumor resection in stage 4S neuroblastoma.
Methods: We investigated a cohort of 172 infants diagnosed with stage 4S neuroblastoma between 1994 and 2013. Of 160 evaluable patients, 62 underwent upfront resection of the primary tumor and 98 did not.