Publications by authors named "A F de Vecchi"
Atrial fibrillation (AF) is the most common heart arrhythmia, linked to a five-fold increase in stroke risk. The left atrial appendage (LAA), prone to blood stasis, is a common thrombus formation site in AF patients. The LAA can be classified into four morphologies: broccoli, cactus, chicken wing and windsock.
View Article and Find Full Text PDFIntroduction: The lymphatic system is a multifaceted regulator of tissue homeostasis and an integral part of immune responses. Previous studies had shown that subsets of lymphatic endothelial cells (LEC) express , an essential component of humoral innate immunity and tissue homeostasis.
Methods: In the present study using whole-mount imaging and image-based morphometric quantifications, -targeted mice and functional analysis, we investigated the involvement of PTX3 in shaping and function of the lymphatic vasculature.
Article Synopsis
- The study aimed to assess disease activity, muscle strength, and functional abilities in newly diagnosed juvenile dermatomyositis (JDM) patients over a 2-year period.
- A total of 96 JDM patients were evaluated at diagnosis and at 6, 12, 18, and 24 months using various clinical assessment tools, showing significant improvements in some areas, particularly in the first 6 months.
- Despite overall improvement in disease activity scores, some measures like childhood myositis and disability indices showed no significant progress, indicating ongoing functional impairment.
Article Synopsis
- * MDCT is crucial for obtaining detailed anatomical information before procedures, aiding in clinical decision-making, and improving patient outcomes while minimizing complications.
- * Key innovations in MDCT, including advanced analytics, patient-specific modeling, and the integration of technologies like 3D printing and artificial intelligence, are transforming patient care for heart valve interventions.
Accurate prenatal diagnosis of coarctation of the aorta (CoA) is challenging due to high false positive rate burden and poorly understood aetiology. Despite associations with abnormal blood flow dynamics, fetal arch anatomy changes and alterations in tissue properties, its underlying mechanisms remain a longstanding subject of debate hindering diagnosis in utero. This study leverages computational fluid dynamics (CFD) simulations and statistical shape modelling to investigate the interplay between fetal arch anatomy and blood flow alterations in CoA.
View Article and Find Full Text PDF