Publications by authors named "A F Zamorano"

Background: Data on maternal and fetal outcomes in patients diagnosed with cancer during pregnancy are limited. Given expected increase in patients diagnosed with cancer during pregnancy, there is a growing need to evaluate clinical outcomes.

Objective: To evaluate obstetric outcomes among women with early-stage gynecologic or breast cancer who were diagnosed during pregnancy compared to women without cancer in a population-based cohort.

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Article Synopsis
  • A study aimed to compare the overall survival rates of patients with early-stage cervical cancer who underwent simple hysterectomy with lymph node staging versus those who had radical hysterectomy with lymph node staging.
  • Researchers analyzed data from the National Cancer Database from 2010 to 2019, matching patients based on various factors such as age, tumor size, and comorbidities.
  • The results found no significant difference in overall survival, readmission rates, or mortality rates between the two surgical approaches, indicating that both procedures may have similar outcomes for early-stage cervical cancer patients.
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While universal tumor testing for Lynch Syndrome (LS) is recommended in all new diagnoses of colorectal cancer (CC) and endometrial cancer (EC), the cost and availability of this test in low-resource settings poses challenges. The PREdiction Model for gene Mutations (PREMM) is a clinical algorithm designed to assess the risk of an individual carrying estimates one's risk of carrying a LS mutation. This study aims to assess the feasibility of using PREMM to screen for LS risk in Guatemala.

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Objective: To examine the impact of the COVID-19 pandemic on cervical cancer screening rates of Hispanic individuals compared to non-Hispanic White (NHW) individuals in the United States, whether a responsive surge in catch-up screenings occurred as society adapted to pandemic changes, and to investigate the sociodemographic characteristics between the study populations.

Methods: Using cross-sectional data from the All of Us Research Program, which incorporates electronic health record data and survey data from a demographically, geographically, and medically diverse participant group, we assessed the annual cervical cancer screening rates during 2019-2021 by race/ethnicity among eligible individuals ages 21-64.

Results: Among 116,052 unique individuals (78,829 NHW and 37,223 Hispanic), Hispanic individuals had lower annual cervical cancer screening rates than NHWI across the three years studied.

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