Publications by authors named "A F Tiburcio"
Objective: To develop a tool that measures levels of adherence to antiretroviral treatment (ART) in resource-poor settings, based on a combination of four methods for measuring adherence.
Methods: Retrospective review of 500 medical records of people living with HIV, randomly selected from October 2017 to January 2020. Adherence to ART was measured by combining four measurement methods (coverage of prescribed ART, ART picked up at pharmacies, viral load, and self-reported adherence).
Diagnostic yield of a multigene sequencing approach in children classified as idiopathic short stature.
Endocr Connect
December 2022
Article Synopsis
- - The study focused on children with idiopathic short stature (ISS) to see if a multigene analysis could provide a genetic diagnosis, as many remain undiagnosed after extensive evaluations.
- - Researchers analyzed 102 children with ISS using targeted panel sequencing, finding pathogenic or likely pathogenic genetic variants in 17 children, resulting in a diagnostic yield of 16.7%.
- - The findings revealed that a multigene sequencing approach can identify genetic causes of short stature, potentially changing the classification of ISS cases and affecting clinical management, especially in those with more severe short stature.
Evaluation of Fourier Transform Infrared Spectroscopy as a First-Line Typing Tool for the Identification of Extended-Spectrum β-Lactamase-Producing Outbreaks in the Hospital Setting.
Front Microbiol
June 2022
Early detection of pathogen cross-transmission events and environmental reservoirs is needed to control derived nosocomial outbreaks. Whole-genome sequencing (WGS) is considered the gold standard for outbreak confirmation, but, in most cases, it is time-consuming and has elevated costs. Consequently, the timely incorporation of WGS results to conventional epidemiology (CE) investigations for rapid outbreak detection is scarce.
View Article and Find Full Text PDFSalt stress is an important factor limiting plant productivity by affecting plant physiology and metabolism. To explore salt tolerance adaptive mechanisms in the model legume we used three genotypes with differential salt-sensitivity: TN6.18 (highly sensitive), Jemalong A17 (moderately sensitive), and TN1.
View Article and Find Full Text PDFSalinity constitutes one of the most important causes leading to severe reduction in plant yield. Several reports correlate the accumulation of polyamines in plants with tolerance to abiotic stress cues. The present study examined three genotypes with differing sensitivities to salinity (TN1.
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