Publications by authors named "A F Sher"

Background: Organic fertilizers are safer and more eco-friendly than chemical fertilizers; hence, organic fertilizers can be used to support sustainable farming. The effects of PGPRs are manifold in agriculture, especially in monoculture crops, where the soil needs to be modified to increase germination, yield, and disease resistance. The objective of this study was to assess the effects of PGPRs combined with fertilizer on the yield and productivity of canola.

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Endophytes are microbes living within plant tissue, with some having the capacity to fix atmospheric nitrogen in both a free-living state and within their plant host. They are part of a diverse microbial community whose interactions sometimes result in a more productive symbiosis with the host plant. Here, we report the co-isolation of diazotrophic endophytes with synergistic partners sourced from two separate nutrient-limited sites.

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  • Neural interfaces can evoke specific neuron responses but often face challenges due to unpredictable nonlinearity when multiple electrodes are stimulated simultaneously.
  • A biophysical model was created to study how retinal ganglion cells (RGCs) respond to this multi-electrode stimulation, and it was validated with real data from macaque retinas recorded through a microelectrode array.
  • The model demonstrated that the positioning of electrodes significantly influences the response, showing that spikes can summate linearly or nonlinearly based on their proximity to the cell body and axon, supporting the hypothesis of multiple spike initiation sites.
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  • Memory-phenotype (MP) CD4 T lymphocytes develop from naïve T cells and can differentiate into various T cell subsets to manage inflammation, especially in low-immune settings.
  • The study highlights that MP lymphocytes are not only made up of T helper 1 (T1) and T helper 17 (T17) cells but also contain a "undifferentiated" subpopulation that has the potential to develop into these functional subsets.
  • The undifferentiated MP lymphocytes possess the ability to proliferate rapidly and can differentiate into T1, T17, and regulatory T cells, which contributes to inflammation, although their response is regulated by existing T cells.
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  • The study challenges the traditional view of retinal ganglion cells (RGCs) in the retina functioning mainly through simple center-surround spatial filtering, revealing instead a much higher functional diversity in primate RGC types, particularly in macaques and humans.
  • Researchers identified 18-27 functional RGC types in primates, along with surprising non-classical receptive field structures and distinct responses to visual stimuli like natural movies.
  • These findings suggest that these diverse RGC types have specialized roles in vision rather than just proportioning visual information at varying spatial scales.
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