Publications by authors named "A F Serre"

Background: Radical prostatectomy (RP) is one possible curative treatment for localized prostate cancer. Despite that, up to 40% of patients will later relapse. Currently, post-operative radiotherapy (PORT) courses deliver 1.

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Objective: Gynecomastia and lipomastia are benign proliferations of the male breast affecting 32-65% of men. Numerous surgical procedures often result in stigmatizing scars when it comes to skin resection. The purpose of this study was to review skin-sparing techniques and to describe our skin-sparing approach to treat skin excess using transcutaneous netting.

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Introduction: Considering the increasing number of conservative surgeries (quadrantectomies) for primary breast carcinoma, especially in the early stages, often followed by adjuvant radiotherapy, the incidence of radiation-associated angiosarcoma (RAS) is expected to rise in the coming decades, and it will represent a clinical and therapeutic challenge, as limited data are available due to the rarity and heterogeneity of the disease. Though the prognosis of these patients is poor, a number of clinical and pathological factors can be evaluated to better understand the course of RAS. The aim of this systematic review is to explore the available clinical-pathological, therapeutic, and prognostic data regarding RAS to evaluate its occurrence, diagnosis, treatment, and outcomes.

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Article Synopsis
  • The study evaluates the effectiveness of a combination treatment involving abiraterone acetate plus prednisone, prostate bed radiotherapy, and goserelin in men experiencing biochemical recurrence after prostatectomy, focusing on the potential role of circulating tumor cells (CTCs).
  • Conducted as a phase 2 trial with 46 participants over a median follow-up of 47 months, the results reported a 3-year biochemical recurrence-free survival rate of 81.5% and an alternative rate of 95.6%.
  • Common side effects included acute issues like pollakiuria during radiotherapy and long-term effects like urinary incontinence, while non-radiotherapy-related side effects included hot flashes and hypertension, with a CTC count ≥5 linked to
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