Improving the thermal performance of PVC windows with pultruded thermoplastic reinforcement.

Today, composite profiles of constant cross section are widely used in advanced engineering structures. The use of composite profiles in window and door structures can reduce thermal bridging and reduce energy consumption for heating and cooling. This article focuses on the production of new, thermoplastic-based structural pultruded profiles and their application in a PVC (polyvinylchloride) window structure as a reinforcement.

Microbial Corrosion of Copper Under Conditions Simulating Deep Radioactive Waste Disposal.

This paper presents the results of microbial corrosion tests on M0-grade copper under conditions simulating a geological repository for radioactive waste at the Yeniseisky site (Krasnoyarsk Krai, Russia). The work used a microbial community sampled from a depth of 450 m and stimulated with glucose, hydrogen and sulfate under anaerobic conditions. It was shown that the maximum corrosion rate, reaching 9.

Pan-cancer analysis of biallelic inactivation in tumor suppressor genes identifies KEAP1 zygosity as a predictive biomarker in lung cancer.

The canonical model of tumor suppressor gene (TSG)-mediated oncogenesis posits that loss of both alleles is necessary for inactivation. Here, through allele-specific analysis of sequencing data from 48,179 cancer patients, we define the prevalence, selective pressure for, and functional consequences of biallelic inactivation across TSGs. TSGs largely assort into distinct classes associated with either pan-cancer (Class 1) or lineage-specific (Class 2) patterns of selection for biallelic loss, although some TSGs are predominantly monoallelically inactivated (Class 3/4).

[The personal support of system of long-term care: potential of care by relatives].

The article examines problems of personnel support of long-term care system. The analysis of main trends in quantitative changes in medical personnel and social workers was carried out. The reduction in the number of paramedical and junior medical personnel, who are the basis for provision of sanitary and hygienic services.