A Modified Mucosal Incision for Easy Entry Into the Submucosal Space During Peroral Endoscopic Myotomy.

A technique of modified mucosal incision is discussed here for easy submucosal entry during peroral endoscopic myotomy (POEM). An L-shaped mucosal incision was used during peroral endoscopic myotomy in six cases of achalasia cardia. The incision was closed by clips in all the cases after the complete myotomy.

A Tracking prior to Localization workflow for Ultrasound Localization Microscopy.

Ultrasound Localization Microscopy (ULM) has proven effective in resolving microvascular structures and local mean velocities at sub-diffraction-limited scales, offering high-resolution imaging capabilities. Dynamic ULM (DULM) enables the creation of angiography or velocity movies throughout cardiac cycles. Currently, these techniques rely on a Localization-and-Tracking (LAT) workflow consisting in detecting microbubbles (MB) in the frames before pairing them to generate tracks.

Dynamic Ultrasound Localization Microscopy Without ECG-Gating.

Objective: Dynamic Ultrasound Localization Microscopy (DULM) has first been developed for non-invasive Pulsatility measurements in the rodent brain. DULM relies on the localization and tracking of microbubbles (MBs) injected into the bloodstream, to obtain highly resolved velocity and density cine-loops. Previous DULM techniques required ECG-gating, limiting its application to specific datasets, and increasing acquisition time.

Equivalent-time-active-cavitation-imaging enables vascular-resolution blood-brain-barrier-opening-therapy planning.

. Linking cavitation and anatomy was found to be important for predictable outcomes in focused-ultrasound blood-brain-barrier-opening and requires high resolution cavitation mapping. However, cavitation mapping techniques for planning and monitoring of therapeutic procedures either (1) do not leverage the full resolution capabilities of ultrasound imaging or (2) place constraints on the length of the therapeutic pulse.

Gel nail polish as an alternative to traditional coverslip sealants: A quick solution to a sticky situation.

A widespread protocol to seal coverslips on a microscope slide for histological analysis utilizes air-drying nail polish. Nail polish is applied to glue the coverslip in place and prevent the leakage of mounting media. Air drying takes time, typically overnight, and generates an unpleasant smell.