[Insulin level, glycemia, insulin resistance and β-cell function in relation to the lifestyle of Arctic indigenous people. Are there conditions for diabetes and which type?].

Background: Modern studies suggest that lifestyle changes of the indigenous Arctic residents lead to the loss of the "adaptive polar type of metabolism", which is characterized by the intensification of protein metabolism, optimization of lipid metabolism, and minimization of carbohydrate metabolism at low insulin concentrations. How to survive the era of change?

Aim: To assess insulinemia, glycemia, β-cell secretory activity, and insulin sensitivity in Arctic indigenous people in relation to their lifestyle.

Materials And Methods: A cross-sectional study of a population of indigenous Arctic residents (Nenets, Komi) aged from 22 to 60 years was conducted.

[24-Hour monitoring of the serum lipid profile in normal and obese women].

In fast and in fat-load elevated the free cholesterol level and decreased the total phospholipids contents in the blood serum of both normal and obese women. Subsequently, normal women revealed a drop in phosphatidylcholine, phosphatidylethanolamine, phosphatidylserine, sphingomyelin, whereas in obese women the phosphatidylcholine level remained stable during the test. Contents of phosphatidylcholine, phosphatic acid and glycerophosphate was still lowering in 24 hours after the fat load.