Publications by authors named "A F Ram"
Background: Undocumented individuals with hematologic malignancies in the United States face barriers to receiving often-curative stem cell transplant (SCT), instead receiving inferior treatment with higher mortality. Federal and state policies' impact on undocumented individuals' lived experiences goes unnoticed.
Objective: To understand the experiences of this rare population of undocumented individuals with hematologic malignancies who cannot receive medically indicated SCT.
Article Synopsis
- Understanding the distribution of the Indian crested porcupine (Hystrix indica) is crucial for conservation efforts in human-dominated landscapes, particularly in the Parsa-Koshi Complex of Nepal.
- Researchers deployed cameras at 154 sites and found moderate occupancy (0.321) and detection probability (0.315) of porcupines, with higher occurrences in protected areas compared to outside.
- The study revealed that porcupine occupancy is positively influenced by agricultural land and human presence, while it decreases with more forest canopy cover, indicating the species' adaptability but also the potential for increased human-wildlife conflicts.
Background: Esophageal cancer (EC) is the sixth leading cause of cancer-related mortality worldwide, continuing to be a significant public health concern. The purpose of this study is to assess the impact of staging and histopathology of EC on associated mortality. The study also aims to further investigate clinical characteristics, prognostic factors, and survival outcomes in patients diagnosed with EC between 2010 and 2017.
View Article and Find Full Text PDFAn Investigation of Nirmatrelvir (Paxlovid) Resistance in SARS-CoV-2 M.
ACS Bio Med Chem Au
December 2024
The high throughput YESS 2.0 platform was used to screen a large library of SARS-CoV-2 M variants in the presence of nirmatrelvir. Of the 100 individual most prevalent mutations identified in the screen and reported here, the most common were E166V, L27V, N142S, A173V, and Y154N, along with their various combinations.
View Article and Find Full Text PDFBackground And Aims: MicroRNAs (miRNAs) are becoming progressively emerging in cancer research from an etiologic and curative point of view. Several miRNAs act as oncogenes or tumor suppressors, which are dysregulated in numerous cancers. Our previous studies have established that nimbolide (a bioactive terpenoid from neem) attenuated hepatocellular carcinoma (HCC) through various mechanisms in mice.
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