Publications by authors named "A F R M Ramsperger"

Article Synopsis
  • * This study primarily focuses on whether primary human macrophages from blood can uptake polystyrene micro- and nanobeads (MNBs) and how they respond to it, by visualizing these processes using advanced microscopy techniques.
  • * Findings revealed that the uptake of MNBs affects the metabolic activity of macrophages in a size- and concentration-dependent manner, increasing necrosis and reactive oxygen species (ROS) production, highlighting the need for further investigation into the effects of plastic pollution on human health.
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Due to the abundance of microplastics in the environment, research about its possible adverse effects is increasing exponentially. Most studies investigating the effect of microplastics on cells still rely on commercially available polystyrene microspheres. However, the choice of these model microplastic particles can affect the outcome of the studies, as even nominally identical model microplastics may interact differently with cells due to different surface properties such as the surface charge.

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Contamination of the environment with nano-and microplastic particles (NMPs) and its putative adverse effects on organisms, ecosystems, and human health is gaining increasing scientific and public attention. Various studies show that NMPs occur abundantly within the environment, leading to a high likelihood of human exposure to NMPs. Here, different exposure scenarios can occur.

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Background: Synthetic polymers (plastics) from fossil resources are produced in large quantities and reach the environment as microplastics due to improper disposal and via various entry routes. This may lead to implications on flora, fauna, and humans.

Objectives: This article aims to provide a concise overview for dermatologists about this complex topic and how it relates to daily medical practice.

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The environmental fate and toxicity of microplastic particles are dominated by their surface properties. In the environment, an adsorbed layer of biomolecules and natural organic matter forms the so-called eco-corona. A quantitative description of how this eco-corona changes the particles' colloidal interactions is still missing.

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