[The biological and diagnostic implication of the comparative data on expression of the same protein, obtained by Western blotting and surface plasmone resonance tests].

The comparative analysis of the data on the expression of the same modulating protein MX, obtained on the same biological materials by Western blotting and surface plasmone resonance tests was shown to provide in most cases a semiquantitative opinion as to modulation of MX affinity to its specific target (effector X protein) under the experimental action of F. This is doubtlessly to offer additional possibilities for the prediction and differential diagnosis of a number of diseases, including cancer.

[Characteristics of polyamine biosynthesis regulation and tumor growth rate in hormone-dependant grafted breast tumors of mice and rats].

Effect of the inhibitors of polyamines biosynthesis on completely or partially hormone-dependant breast tumors (mouse Ca755 carcinoma and Walker W-256 carcinosarcoma) is essentially special: in contrary to hormone-dependant tumors, this effect may be not only breaking but stimulating as well. Change-over from one to another mode of reaction is conditioned, most probable, by hormonal status, which is determined by one or another estral cycle phase. Biochemical mechanisms of this change-over are closely connected with polyamines metabolism, namely the degree of polyamines (especially spermine) interconvertion and physiological reactivity level of the system controlling expression of ornithin-decarboxilase.

[A comparative study of the asymmetry in the spatial-exploratory behavior of mice in 2 populations].

In two populations of contemporary generations of non-strain mice was found a considerable shift of interhemispheric asymmetry the relative activity of the right hemisphere being increased in comparison with the known data. Quantitative evaluation and the character of this shift in the two populations were different. Changes observed are suggested to be a manifestation of adaptive response of the organism to environmental pollution.

[The effect of peripheral cholinergic blockers on the cocarcinogenic action of an experimental influenza infection].

The cocarcinogenic effect of chronic influenza infection was shown to be mediated by M-cholinergic structures. Administration of a M-anticholinergic agent in low dose at the key stages of chronic influenza infection development was followed by a nearly complete suppression of its cocarcinogenic action. N-anticholinergic agents failed to exert such effect.