Publications by authors named "A F Oluwole"

A novel GO/BiVO/AgCrO heterojunction photocatalyst was prepared by depositing AgCrO on the highly active (040) facet of BiVO, followed by incorporating graphene oxide (GO) through an precipitation method. This synergistic modification of BiVO by AgCrO and GO results in excellent photocatalytic performance, with a degradation efficiency of 94.6% coupled with a maximum rate constant of 0.

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Article Synopsis
  • - The peptidoglycan pathway, crucial for bacterial cell wall formation, targets the translocation of undecaprenyl phosphate (C-P) across the membrane, which is facilitated by proteins like DedA and UptA.
  • - Research using native mass spectrometry reveals that UptA binds C-P more effectively than shorter-chain lipid analogs and interacts in a pH-sensitive manner.
  • - The study also finds that certain lipopeptide antibiotics can inhibit UptA by competing for its binding site, suggesting potential directions for developing new antibiotics that target lipid recycling processes in bacteria.
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Clavulanic acid is a medicinally important inhibitor of serine β-lactamases (SBLs). We report studies on the mechanisms by which clavulanic acid inhibits representative Ambler class A (TEM-116), C (Escherichia coli AmpC), and D (OXA-10) SBLs using denaturing and non-denaturing mass spectrometry (MS). Similarly to observations with penam sulfones, most of the results support a mechanism involving acyl enzyme complex formation, followed by oxazolidine ring opening without efficient subsequent scaffold fragmentation (at pH 7.

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Lipid-protein interactions play a multitude of essential roles in membrane homeostasis. Mitochondrial membranes have a unique lipid-protein environment that ensures bioenergetic efficiency. Cardiolipin (CL), the signature mitochondrial lipid, plays multiple roles in promoting oxidative phosphorylation (OXPHOS).

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The high burden of anaemia during pregnancy underscores the urgent need to gain a comprehensive understanding of the factors contributing to its widespread occurrence. Our study assessed the prevalence and the trends of moderate-to-severe anaemia (MSA) in late pregnancy (28 to 36 weeks) and then investigated the key determinants driving this prevalence among women in Lagos, Nigeria. We conducted a secondary data analysis involving 1216 women enrolled in the Predict-PPH study between January and March 2023.

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