A novel GO/BiVO/AgCrO heterojunction photocatalyst was prepared by depositing AgCrO on the highly active (040) facet of BiVO, followed by incorporating graphene oxide (GO) through an precipitation method. This synergistic modification of BiVO by AgCrO and GO results in excellent photocatalytic performance, with a degradation efficiency of 94.6% coupled with a maximum rate constant of 0.
View Article and Find Full Text PDFProc Natl Acad Sci U S A
October 2024
Clavulanic acid is a medicinally important inhibitor of serine β-lactamases (SBLs). We report studies on the mechanisms by which clavulanic acid inhibits representative Ambler class A (TEM-116), C (Escherichia coli AmpC), and D (OXA-10) SBLs using denaturing and non-denaturing mass spectrometry (MS). Similarly to observations with penam sulfones, most of the results support a mechanism involving acyl enzyme complex formation, followed by oxazolidine ring opening without efficient subsequent scaffold fragmentation (at pH 7.
View Article and Find Full Text PDFLipid-protein interactions play a multitude of essential roles in membrane homeostasis. Mitochondrial membranes have a unique lipid-protein environment that ensures bioenergetic efficiency. Cardiolipin (CL), the signature mitochondrial lipid, plays multiple roles in promoting oxidative phosphorylation (OXPHOS).
View Article and Find Full Text PDFThe high burden of anaemia during pregnancy underscores the urgent need to gain a comprehensive understanding of the factors contributing to its widespread occurrence. Our study assessed the prevalence and the trends of moderate-to-severe anaemia (MSA) in late pregnancy (28 to 36 weeks) and then investigated the key determinants driving this prevalence among women in Lagos, Nigeria. We conducted a secondary data analysis involving 1216 women enrolled in the Predict-PPH study between January and March 2023.
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