[Content of arachidonic acid metabolites in blood and saliva of children with bronchial asthma].

The rise of the thromboxane B2, leukotriene B4 and prostaglandin F2a concentration in the blood and saliva of children was revealed during the attack of the bronchial asthma. At the same time the content of the prostaglandin E2 and prostacyclin in these biological fluids was reduced. The level of the eicosanoids in the examined liquids was correlated with the severity of bronchial asthma proceeding and with the adrenal glands function, which activity was also reduced.

[The characteristics of the adaptive-recovery reactions of children after lung resection in chronic respiratory organ diseases].

The results of examination of 80 children at the late postoperative period are indicative of gradual progression of the reparative-restorative processes 1 year after the operation already. Diffuse purulent endobronchitis preserves for one year, purulent endobronchitis on the non-operated side-up to 3 years, at a zone of the operative intervention, local inflammatory process is defined more than 3 years later. In half of the children operated on, exacerbations of the bronchial tree disease with formation in some of them of the combined changes in hemodynamics and external respiration were revealed.

[Effect of maternal genotype characteristics on fetal adaptation to intra- and extrauterine conditions].

Effects of the maternal genotype on the fetal and neonatal compensatory-adaptive patterns have been examined in 1396 newborns. Correlations were found between the ante- and intrapartum progress, physical development of the newborns, early neonatal course and the maternal phenotype. Maternal-fetal compatibility was found to influence the neonatal status and later morbidity and mortality.