Publications by authors named "A F Massoud"
Recently, it has been well-established that the glymphatic or glial-lymphatic system plays a vital role in the pathophysiology of various neurological compromise, especially hydrocephalus (HCP). Till now, the complete pathway is not yet fully understood, and little evidence is available from the literature that links hydrocephalus to disorders of the glymphatic system. Most published molecular studies and animal research have shown that, in models with hydrocephalus, the drainage of cerebrospinal fluid (CSF) via the glymphatic system is disrupted.
View Article and Find Full Text PDFConservative laparoscopic torsioning with or without cystectomy or oophoropexy has emerged as a promising approach for the management of ovarian torsion, particularly in pediatric populations. We sought to understand the efficacy of this approach. We comprehensively reviewed the relevant literature.
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- Crocin nanoparticles (CRO-NPs) were developed to improve the bioavailability and anticancer effects of crocin, a saffron antioxidant, when combined with doxorubicin (DOX) chemotherapy on liver cancer and non-cancerous cells.
- Characterization of CRO-NPs showed better stability and a much smaller size, resulting in significantly greater antitumor effects against HepG2 cells compared to native crocin.
- The study found that CRO-NPs increased apoptosis in cancer cells and led to cell cycle arrest, while also enhancing the expression of key apoptotic and autophagic genes when used with DOX, without causing harm to non-cancerous WI38 cells.
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- In May 2023, the FDA approved a Pfizer-sponsored bivalent RSV vaccine (AbrysvoTM) for use in pregnant women to prevent RSV infections in newborns, following safety concerns that halted GSK trials in 2022.
- A comprehensive evaluation of randomized controlled trials (RCTs) showed several maternal side effects were more common with the RSVpreF vaccine, including local reactions, fatigue, and joint pain.
- Despite increased side effects, the vaccine significantly reduced cases of RSV-related lower respiratory tract disease and hospitalizations, but there was a notable rise in the risk of preterm delivery associated with its use.
This paper expands a recently proposed peak current-mode (PCM) control method for a power factor correction (PFC) boost converter to include the totem-pole converter and solves the controller's compatibility problem with the totem-pole converter by proposing three input current sensing methods. Using MATLAB/Simulink 2023b, simulation experiments on a 2 kW totem-pole converter utilizing the PFC PCM controller were carried out to assess the performance of the controller with the proposed sensing methods. The findings indicate that under steady-state conditions, all three proposed sensing methods performed input current shaping successfully and yielded nearly identical THD% of about 4.
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