Restrictive guideline reduces platelet count thresholds for transfusions in very low birth weight preterm infants.

Background And Objectives: Platelet transfusions are performed almost entirely according to expert experience. This study assessed the effectiveness of a restrictive guideline to reduce platelet transfusions in preterm infants.

Methods: A retrospective cohort of preterm infants with a birth weight of <1500 g had been born in 2 periods.

A very strict guideline reduces the number of erythrocyte transfusions in preterm infants.

Background And Objectives: Benefits of adopting restrictive guidelines for erythrocyte transfusions are still controversial. The objective of this study was to verify if a very strict guideline could reduce erythrocyte transfusions in preterm infants without adverse outcomes.

Materials And Methods: Two prospective cohorts of neonates with gestational age < 37 weeks and birth weight < 1500 g were studied.