Publications by authors named "A F K Bakre"
Article Synopsis
- PFAS are man-made chemicals found in many industries that pose environmental and public health risks, but monitoring them in Africa is hindered by a lack of mass spectrometry (MS) instruments.
- The review highlights that few African countries have adequate access to MS, leading to significant underreporting of PFAS data and related health issues.
- To improve monitoring efforts, the study calls for financial support for MS instruments, the establishment of regional centers of excellence, and investment in training programs for effective PFAS management.
Rapidly identifying and sequencing viral pathogens in poultry flocks can substantially reduce economic loss especially during disease outbreaks. Current next generation sequencing technologies require multi-step laboratory-intensive workflows to generate sequence data which precludes field adaptation. In this study, we hypothesized that direct RNA sequencing (DRS) using an Oxford Nanopore Technology (ONT) MinION device would enable sequencing of the full-length viral RNA genome of Orthoavulavirus javaense (OAVJ), the causative of Newcastle disease, a major poultry challenge.
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- Lassa fever (LF) is a viral hemorrhagic illness that is increasing in reported cases in Nigeria and is also endemic in West African countries.
- The study analyzed LF epidemiology data from Nigeria’s Centre for Disease Control and examined the genetic sequences of the virus to understand its evolution and outbreaks.
- To address the rising cases of LF, the study recommends enhancing diagnostic capabilities, raising public health awareness, implementing integrated surveillance, and supporting vaccine research in Africa.
Post-transcriptional gene regulation mediated by microRNAs (miRNAs) relies on sequence complementarity between the miRNA seed site and the target gene transcript(s). This complementarity can completely inhibit or reduce translation into protein. We hypothesized that viruses employ sequence complementarity/similarity with host miRNAs to inhibit or increase the miRNA-mediated regulation of host gene expression specifically during viral infection(s).
View Article and Find Full Text PDFMeat handling is a crucial aspect of public health as it forms complex interactions among humans, animals, and the environment. African meat handlers continue to face various challenges in slaughterhouses that significantly impact their lives and the general public during meat processing. This paper reviews the challenges meat handlers encounter and the associated risks of improper meat handling in various African slaughterhouses.
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