Publications by authors named "A F Ghiam"
Purpose: Active surveillance for prostate cancer relies on regular prostate specific antigen tests and surveillance biopsies. Compliance rates with biopsies vary but the subsequent impact on oncologic outcomes is not known. The objective of this study was to determine whether noncompliance with the confirmatory biopsy negatively impacts prostate cancer specific outcomes.
View Article and Find Full Text PDFPurpose: Quality of life (QOL) for patients with oropharyngeal squamous cell cancer is negatively affected by conventional radiation (RT) owing to radiation exposure to normal tissues. Proton therapy, via pencil beam scanning (PBS), can better spare many of these tissues, and may thereby improve QOL.
Patients And Methods: Patient-reported outcomes were prospectively collected from patients treated from April 2013 to April 2015.
Palliative radiotherapy is an effective treatment in alleviating many symptoms of advanced cancer. Short courses of radiotherapy provide rapid symptom relief and minimize impact on patients. Patients referred for palliative radiotherapy have many concerns beyond radiotherapy; often, these concerns are not fully addressed in traditional radiotherapy clinics.
View Article and Find Full Text PDFArticle Synopsis
- A study was conducted on patients with head and neck carcinoma of unknown primary (HNCUP) who underwent transoral robotic surgery (TORS) and subsequently received either pharyngeal-sparing radiation therapy (PSRT) or pharyngeal-targeted radiation therapy (PRT).
- The results indicated no significant differences in disease outcomes between the PSRT and PRT groups, but PSRT showed significantly reduced treatment-related side effects and complications.
- The conclusion suggests that PSRT may be a safer option with less toxicity for patients after TORS, without compromising effectiveness in disease control compared to PRT.
Background: For patients with head and neck squamous cell carcinoma (SCC) undergoing surgery followed by postoperative radiotherapy (PORT), time from surgery to completion of adjuvant therapy, "package time" impacts locoregional control (LRC). However, the significance of package time in HPV+ oropharyngeal SCC (OPSCC) is unknown.
Methods: We examined patients undergoing TORS resection with PORT for HPV+ OPSCC from January 2010 to December 2015 with ≥18 months follow-up (n = 267).