Publications by authors named "A F Fernandes"

Rational & Objective: Data are limited regarding the long-term efficacy of tolvaptan in adults aged 18-35 years with autosomal dominant polycystic kidney disease (ADPKD) at increased risk of rapid progression. We assessed the effects of tolvaptan within a larger population of younger adults and over longer follow-up than individual clinical trials could provide.

Study Design: Pooled database study.

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Article Synopsis
  • Breastfeeding has numerous health benefits for both mothers and newborns, acting as a protective factor against infant illness and mortality.
  • The study aimed to compare obstetric outcomes between women who breastfed and those who did not, using data from two different time periods: during the pandemic and pre-pandemic.
  • Results indicated that fewer women breastfed within the first hour after delivery during the pandemic, with non-infected mothers having better outcomes regarding vaginal delivery and breastfeeding compared to infected or suspected cases.
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Background: Clinically significant macular edema (CME) is the leading cause of visual loss after ophthalmologic surgery due to the release of inflammatory mediators promoted by the procedures. We aimed to evaluate the outcomes of intravitreal Ozurdex (700 µg dexamethasone) implants as a primary therapeutical option for post-surgical macular edema cases.

Methods: Patients with post-surgical macular edema diagnosed by optical coherence tomography (Cirrus SD-OCT) and treated with Ozudex were selected for the current study.

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Inhalation of crystalline silica particles causes silicosis, which is a severe inflammatory lung disease that is associated with granulomatous and fibrotic responses. We investigated whether silica-induced silicosis might promote airway hyperreactivity (AHR) and the role of TNF-α and thalidomide in this process. Mice received an intranasal instillation of silica particles (1.

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has wild habits with ecological plasticity in anthropized environments. We report the occurrence of this species in several types of artificial containers in 2 fragments of the Atlantic Forest in the city of São Paulo, Brazil. A total of 1,428 larvae were collected, in which plastic containers had the highest abundance of immature forms of Li.

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