Understanding Therapeutic Experience: A Qualitative Evaluation of Virtual and In-Person Treatment.

Introduction Following the COVID-19 pandemic, there was adoption of virtual psychotherapy. There are a number of benefits and drawbacks to telehealth video conferencing that are experienced by both clients and clinicians. The current qualitative study sought to outline the advantages and disadvantages that clients and clinicians have personally experienced in virtual versus in-person therapy in an effort to identify the reasons for which one medium may be preferred over another.

Ofatumumab-associated colitis: A case report.

Background: Colitis has been reported with some anti-CD20 therapies in multiple sclerosis (MS), but not previously with ofatumumab.

Objectives: To report the first case of ofatumumab-associated colitis in MS and discuss its implications.

Methods: Case report.

Mortality burden from variation in provision of surgical care in emergency general surgery: a cohort study using the National Inpatient Sample.

Background: The decision to undertake a surgical intervention for an emergency general surgery (EGS) condition (appendicitis, diverticulitis, cholecystitis, hernia, peptic ulcer, bowel obstruction, ischemic bowel) involves a complex consideration of factors, particularly in older adults. We hypothesized that identifying variability in the application of operative management could highlight a potential pathway to improve patient survival and outcomes.

Methods: We included adults aged 65+ years with an EGS condition from the 2016-2017 National Inpatient Sample.

Per- and polyfluoroalkyl substances alter innate immune function: evidence and data gaps.

Per- and polyfluoroalkyl substances (PFASs) are a large class of compounds used in a variety of processes and consumer products. Their unique chemical properties make them ubiquitous and persistent environmental contaminants while also making them economically viable and socially convenient. To date, several reviews have been published to synthesize information regarding the immunotoxic effects of PFASs on the adaptive immune system.

Examining the impact of COVID-19 disruptions on population-based breast cancer screening in Ireland.

Objective: Many population-based breast screening programmes temporarily suspended routine screening following the COVID-19 pandemic onset. This study aimed to describe screening mammography utilisation and the pattern of screen-detected breast cancer diagnoses following COVID-19-related screening disruptions in Ireland.

Methods: Using anonymous aggregate data from women invited for routine screening, three time periods were examined: (1) January-December 2019, (2) January-December 2020, and (3) January-December 2021.