Publications by authors named "A F Appiah"
Article Synopsis
- Abemaciclib, a CDK4/6 inhibitor, has shown promise in treating metastatic castration-resistant prostate cancer (mCRPC), potentially shifting treatment approaches similar to its use in breast cancer.
- In a study involving 44 patients with mCRPC who had previously undergone multiple treatments, the primary goal was to report the objective response rate (ORR), which was found to be 6.8%, with a disease control rate of 45.5%.
- The treatment was generally well tolerated, with manageable side effects, and provided preliminary evidence supporting CDK4/6 as a therapeutic target in prostate cancer.
This study was aimed at using microcosm experiments to assess crude oil degradation efficiency of and isolated along Ghana's coast. Uncontaminated seawater from selected locations along the coast was used to isolate bacterial species by employing enrichment culture procedures with crude oil as the only carbon source. The isolates were identified by means of the extended direct colony transfer method of the Matrix Assisted Laser Desorption Ionization Time of Flight Mass Spectroscopy (MALDI-TOF MS), as , and .
View Article and Find Full Text PDFRemediating vanadium (V) polluted soil has garnered widespread attention over the past decade. Yet, few research projects have investigated the stabilization of soil V using modified biochar, so the effects and interacting mechanisms between soil properties and modified biochar for V immobilization and stabilization remain unclear. Hence, this gap is addressed by determining the leaching behavior and mechanisms of soil V on different dosages of phosphoric acid (HPO) impregnated biochar (MLBC, 0.
View Article and Find Full Text PDFBackground: This study aimed to determine the effectiveness of a standardized trauma intake form (TIF) to improve achievement of key performance indicators (KPIs) of initial trauma care among injured children, compared to adults, at non-tertiary hospitals in Ghana.
Methods: A stepped-wedge cluster randomized trial was performed with research assistants directly observing the management of injured patients before and after introducing the TIF at emergency units of 8 non-tertiary hospitals for 17.5 months.
Effect of HIV infection on plasma exposure to first-line TB drugs and target attainment in children.
Int J Tuberc Lung Dis
December 2023
Whether HIV infection adversely affects exposure to first-line TB drugs in children is debatable. It is also not known whether HIV infection increases the risk of plasma underexposure or overexposure to TB drugs. This study sought to address these questions.
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