The healthy human gut can take it all: vancomycin-variable, linezolid-resistant strains and specific bacteriocin-species interplay in spp.

spp. are opportunistic human pathogens colonizing the human gut and a significant reservoir for the continuous adaptation of hospital clones. However, studies on the features of enterococci species co-colonizing healthy individuals are scarce.

Prevalence of hospital malnutrition in patients using nutritional support.

Objective: To investigate the prevalence of malnutrition in hospitalized patients using nutritional support, considering it's difficult to achieve nutritional goal and great risk to increase malnutrition.

Methods: A cross-sectional study with 102 patients over 18 years in use of enteral and/or parenteral nutritional therapy and monitored by the Nutritional Therapy Committee between December 2021 and August 2022. All data were collected from electronic medical records.

Bacteriocin distribution patterns in and : bioinformatic analysis using a tailored genomics framework.

Unlabelled: Multidrug-resistant strains represent a major concern due to their ability to thrive in diverse environments and cause life-threatening infections. While antimicrobial resistance and virulence mechanisms have been extensively studied, the contribution of bacteriocins to 's adaptability remains poorly explored. , within the Bacillota phylum, is a prominent bacteriocin producer.

Interactions between commensal and and clinical isolates of .

() is a versatile pathogen, responsible for multidrug-resistant infections, especially in hospitalized immunocompromised patients. Its population structure has been characterized by diverse clades (A1, A2, and B (reclassified as ()), adapted to different environments, and distinguished by their resistomes and virulomes. These features only partially explain the predominance of clade A1 strains in nosocomial infections.

BDNF-dependent signaling in the olfactory bulb modulates social recognition memory in mice.

An operative olfactory bulb (OB) is critical to social recognition memory (SRM) in rodents, which involves identifying conspecifics. Furthermore, OB also allocates synaptic plasticity events related to olfactory memories in their intricate neural circuit. Here, we asked whether the OB is a target for brain-derived neurotrophic factor (BDNF), a well-known mediator of plasticity and memory.