Background: Stress associated with changes in host immunity occurs in response to altered environmental conditions, endogenous imbalances, infectious agents and harmful stimuli. The importance of genetic diversity in chickens has increased due to individual immune differences towards resistance and susceptibility to various stimuli.
Objectives: This study aimed to investigate the association of major histocompatibility complex (MHC) polymorphism with acute phase response (APR) in Ross 308 broiler chickens.
Pharmacol Res Perspect
August 2024
Contrast-induced nephropathy (CIN) is a serious complication that occurs subsequent to the administration of contrast media for therapeutic angiographic interventions. As of present, no effective therapy exists to prevent its occurrence. This single-center double-blind randomized controlled trial aimed to evaluate the effect of edaravone, an antioxidant, in a group of high-risk patients undergoing coronary angiography.
View Article and Find Full Text PDFBackground: Major histocompatibility complex (MHC) is the best characterised genetic region associated with adaptive immune responses, including humoral and cell-mediated immunities.
Objectives: In this study, the association of MHC class II alleles with inflammatory cytokines and acute-phase proteins was evaluated in sheep population.
Methods: Allelic diversity of second exon of ovine DRB1 locus (Ovar-DRB1.
Background: Maedi-Visna (MV) is a progressive lymphoproliferative viral disease that affects multiple organs of small ruminants, including sheep and goats. The disease occurs primarily in the lung tissue and causes interstitial pneumonia.
Aims: The aim of present study was to investigate the prevalence of ovine MV infection in Iranian sheep population through macroscopic, histopathological, serological, and molecular assays, as well as transmission electron microscopy (TEM).
Backgrounds: The development of a canine-specific method of immunocontraception is one of the non-invasive controlling strategies for humanely decreasing the dog population. This study was aimed to investigate the potential of whole sperm in stimulating the immune system and producing specific anti-sperm antibodies (ASAs) in female dogs. Mature, mixed-breed bitches were subcutaneously immunized with high (200 × 10 cells/mL) and low (100 × 10 cells/mL) doses of sperm vaccine, emulsified with Freund's adjuvants.
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