Publications by authors named "A Eskandari"
Three species of the family Sphaerolaimidae were found and are described for the first time along the coast of the Qeshm Island. Sphaerolaimus qeshmensis sp. n.
View Article and Find Full Text PDFControllable surface modification of nanoparticulate drug delivery vectors is key to enhancing specific desirable properties such as colloidal stability, targeting, and stimuli-responsive cargo release. Metal-organic frameworks (MOFs) have been proposed as potential delivery devices, with surface modification achieved by various bioconjugate "click" reactions, including copper-catalysed and strain-promoted azide-alkyne cycloaddition. Herein, we show that photo-induced nitrile imine-mediated tetrazole-ene cycloaddition (NITEC) can be used to surface-modify tetrazole-appended Zr MOFs with maleimides, and vice versa, with the extent of this traceless surface functionalisation controlled by the length of photoirradiation.
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- A new method for extracting and separating compounds from complex mixtures was developed using a circular chip and centrifugal force, enhancing the efficiency of microsolid phase extraction and chromatography.
- The technique utilizes rice husk to create an effective sorbent for model drugs curcumin and phenazopyridine, and evaluates extraction factors using the one-variable-at-a-time method.
- Results showed strong correlations between analyte concentration and detection intensities, with low limits of detection and high recovery rates in urine samples, indicating the method's reliability and effectiveness.
Aphasia profiles and trajectories in acute ischemic stroke: An observational study.
J Stroke Cerebrovasc Dis
January 2025
Article Synopsis
- In a study of acute ischemic stroke (AIS) patients with pure aphasia, researchers analyzed the short-term course and predictors of persistent aphasia and functional outcomes.
- Out of 4513 AIS patients, only 131 had pure aphasia, and among those, 28.4% continued to experience significant aphasia in the subacute phase.
- Factors like stroke mechanism (cardioembolic or atheromatous) and executive function deficits predicted persistent aphasia, while being female and having ongoing aphasia were linked to poorer outcomes at 3 months.
This study assessed the effect of a small-torque generating passive back-support exoskeleton during a low demanding occupational task, namely a repetitive lifting/lowering of an empty crate between the knee and shoulder heights. A comprehensive set of outcomes was considered, ranging from the measured trunk muscle activation and trunk movement to the estimated muscle group forces/coordination, spine loading and spine stability, using a dynamic subject-specific EMG-assisted musculoskeletal model. The exoskeleton decreased back muscle activation and corresponding muscle forces in the lowering phase and reduced spinal loading at larger trunk flexion angles (decreased peak compression and shear forces by ∼ 15%).
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