Publications by authors named "A Epp"
Article Synopsis
- The study compares the safety and efficiency of ambulatory gynecologic procedures done under conscious sedation and local anesthesia at two Canadian institutions over one year.
- It analyzed data from 2,593 patients, finding similar lead times but different procedural times and minor complication rates between the two sites.
- The results support the effectiveness of a common ambulatory care model for minor gynecologic procedures, suggesting it could be replicated across Canada.
Background: SGN-B7H4V is a novel investigational vedotin antibody-drug conjugate (ADC) comprising a B7-H4-directed human monoclonal antibody conjugated to the cytotoxic payload monomethyl auristatin E (MMAE) via a protease-cleavable maleimidocaproyl valine citrulline (mc-vc) linker. This vedotin linker-payload system has been clinically validated in multiple Food and Drug Administration approved agents including brentuximab vedotin, enfortumab vedotin, and tisotumab vedotin. B7-H4 is an immune checkpoint ligand with elevated expression on a variety of solid tumors, including breast, ovarian, and endometrial tumors, and limited normal tissue expression.
View Article and Find Full Text PDFNurses and nursing students may need help understanding the connection between research and practice. Nursing students and clinical nurse leaders worked together to review institutional policies and make recommendations based on the strongest research evidence. In this column, the authors describe how they created a meaningful connection between research and clinical nursing practice for undergraduate nursing students and the benefits to the health system from this innovative program.
View Article and Find Full Text PDFPurpose: The aim of this study was to evaluate the long-term effectiveness and acceptance of the active middle ear implant system Vibrant Soundbridge (VSB, MED-EL, Austria) in patients with aural atresia or aplasia (children and adults).
Methods: Data from 51 patients (mean age 13.9 ± 11.