Publications by authors named "A Enrico"

Article Synopsis
  • Systemic therapy for multiple myeloma (MM) has advanced, but access varies widely across Latin America, especially between public and private healthcare sectors.
  • A study involving 1,029 MM patients from five Latin American countries revealed that those in private institutions generally had better prognostic features and treatment options compared to those in public institutions.
  • The median overall survival was lower for patients in public institutions (44.6 months) compared to those in private institutions (53.3 months), highlighting significant disparities in MM management across the region.
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Article Synopsis
  • The immune system in chronic myeloid leukemia (CML) patients is significantly weakened, affecting their ability to respond to tumors, but shows improvement following effective treatment with tyrosine kinase inhibitors like imatinib.
  • A study analyzed gene expression of various immune mediators in 171 blood samples from CML patients over their first year on imatinib, comparing it with samples from healthy donors.
  • Results indicated that most immune mediators initially declined but largely normalized over time, while also revealing different patterns in optimal versus non-optimal treatment responders.
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Organic electrochemical transistors (OECTs) are promising devices for bioelectronics, such as biosensors. However, current cleanroom-based microfabrication of OECTs hinders fast prototyping and widespread adoption of this technology for low-volume, low-cost applications. To address this limitation, a versatile and scalable approach for ultrafast laser microfabrication of OECTs is herein reported, where a femtosecond laser to pattern insulating polymers (such as parylene C or polyimide) is first used, exposing the underlying metal electrodes serving as transistor terminals (source, drain, or gate).

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