Publications by authors named "A El-Shershaby"
Article Synopsis
- - The study focuses on Hyalomma dromedarii ticks, which are significant for transmitting pathogens to large animals in Egypt, especially as camels and cattle are imported from neighboring countries.
- - Researchers analyzed the transcriptome of these ticks by examining mixed mRNAs from various life stages (eggs, larvae, nymphs, and both fed and unfed adults) to understand the biochemical interactions that take place during tick feeding.
- - The results included a comparison of identified sequences with databases to identify potential protein functions and properties, setting the stage for further understanding of tick physiology and its implications for disease transmission in livestock.
Article Synopsis
- Monoclonal IgY antibodies are gaining popularity due to their high specificity and scalability, making them a strong alternative to traditional polyclonal IgY antibodies.
- The text outlines the production and purification methods of monoclonal IgY antibodies, emphasizing their advantages, such as superior reliability and cost-effectiveness, especially in low- and middle-income countries.
- It concludes by noting the significant benefits of monoclonal IgY antibodies for diagnostics, therapeutics, and research, while also addressing future challenges in the field.
Pasteurella multocida is affecting a multitude of animals and severely affects livestock production. Existing vaccines are mostly chemically inactivated and do not lead to wide protection. Irradiated vaccines are enjoying a renaissance and the concept of "replication defficient but metabolically active" vaccines was recently evaluated in several vaccine trials.
View Article and Find Full Text PDFExposure to gamma rays from cobalt 60 (Co) can induce a complete inactivation of Mannheimia haemolytica. The inactivated bacterial pathogen is a potential vaccine candidate for immunization of ruminants such as sheep. The subcutaneous administration of irradiated vaccine in a two-dose regimen (4.
View Article and Find Full Text PDFSeveral diagnostic measures have been employed to precisely detect the SARS-CoV-2 viral infection using viral antigens, nucleic acids, and other serological approaches. The sensitivity and specificity of the serological tests remain a challenging need. Here, we describe the detection of human anti-SARS-CoV-2 IgG and IgM antibodies qualitatively through two optimized in-house ELISA and lateral flow immunoassay.
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