Route of Feeding as a Proxy for Dysphagia After Stroke and the Effect of Transdermal Glyceryl Trinitrate: Data from the Efficacy of Nitric Oxide in Stroke Randomised Controlled Trial.

Post-stroke dysphagia is common, associated with poor outcome and often requires non-oral feeding/fluids. The relationship between route of feeding and outcome, as well as treatment with glyceryl trinitrate (GTN), was studied prospectively. The Efficacy of Nitric Oxide in Stroke (ENOS) trial assessed transdermal GTN (5 mg versus none for 7 days) in 4011 patients with acute stroke and high blood pressure.

Infections Up to 76 Days After Stroke Increase Disability and Death.

Early infection after stroke is associated with a poor outcome. We aimed to determine whether delayed infections (up to 76 days post-stroke) are associated with poor outcome at 90 days. Data came from the international Efficacy of Nitric Oxide Stroke (ENOS, ISRCTN99414122) trial.

Antisperm antibodies and human infertility.

In a trial to evaluate the role of antisperm antibodies in human infertility, 120 couples (30 normal controls and 90 suffering from various types of infertility) were examined for the presence of agglutinating antibodies (by the Kibrick and Franklin-Dukes methods) and immobilizing antibodies in the serum, cervical mucus, and seminal plasma. In the male partners the highest and most significant incidence was found in the serum and seminal plasma of the group with poor sperm motility. In the female partners the highest and most significant incidence was found in the serum and cervical mucus of the group with unexplained infertility.

Effect of some heterocyclic compounds on human semen composition and biology.

The effect of some heterocyclic compounds on some aspects of human semen metabolism was studied. Caffeine produced stimulation of motility and lactic acid production and an inhibition of fructose utilization and oxygen uptake. Nicotinamide and riboflavin produced stimulation of motility, fructose utilization and oxygen uptake and an inhibition of lactic acid production.