Sleep and cardiac rhythm in healthy men.

Cardiac rhythm during sleep was analysed in 168 healthy men aged 19 to 30 (mean 21.8) years using continuous nocturnal ECG recordings. Thirty five of the subjects were endurance athletes; 99 were recorded at home and 69 at a garrison during military service.

Quinapril and blood lipids.

To assess the effects of angiotensin-converting enzyme inhibition with quinapril on blood lipid profile, serum total cholesterol and triglycerides, together with high-density and low-density lipoprotein cholesterol were analysed in 23 hypertensive patients receiving either placebo (7 patients) or quinapril hydrochloride (16 patients). After 12 weeks of therapy there were no significant changes in blood lipids in either group. No unfavourable changes in blood lipid profile were observed even after 1 year of therapy with quinapril hydrochloride in 13 patients.

The Finnish sauna and cardiovascular diseases.

From time to time it has been claimed that the thermal stress caused by sauna bathing can be harmful to persons with cardiovascular disorders. Furthermore, elderly persons in general, who have experienced no symptoms from bathing, have also been cautioned. However, several studies carried out in Finland did not confirm the adverse effects of bathing on the elderly and cardiovascular patients.

Antihypertensive and biochemical effects of different doses of hydrochlorothiazide alone or in combination with triamterene.

The antihypertensive and biochemical effects of 25 mg hydrochlorothiazide alone or 50 mg hydrochlorothiazide alone or in combination with triamterene (either 37.5 or 75 mg) once daily were studied in 26 patients with essential hypertension. After a 5-week run-in period the patients were randomized to receive active therapy in a cross-over manner.