Sensitivity and specificity of International Classification of Diseases algorithms (ICD-9 and ICD-10) used to identify opioid-related overdose cases: A systematic review and an example of estimation using Bayesian latent class models in the absence of gold standards.

Objectives: This study aimed to summarize validity estimates of International Classification of Diseases (ICD) codes in identifying opioid overdose (OOD) among patient data from emergency rooms, emergency medical services, inpatient, outpatient, administrative, medical claims, and mortality, and estimate the sensitivity and specificity of the algorithms in the absence of a perfect reference standard.

Methods: We systematically reviewed studies published before December 8, 2023, and identified with Medline and Embase. Studies reporting sufficient details to recreate a 2 × 2 table comparing the ICD algorithms to a reference standard in diagnosing OOD-related events were included.

Pediatric maxillofacial and oral traumatological emergencies in the department of stomatology, maxillofacial and plastic surgery of the university hospital of cocody (republic of IVORY COAST).

Introduction: Maxillofacial and oral trauma in children are a frequent reason for consultation in stomatology and maxillofacial surgery.

Patients And Methods: Retrospective study with a descriptive aim, carried out on the basis of an analysis of the physical medical files of cases of maxillofacial and oral trauma admitted to the stomatological emergencies of the university hospital center of cocody over a period of 04 years (January 2016 to December 2019).

Results: The average age of the patients was 7.

Effects of subacute oral administration of aqueous extract of Müll.Arg (Euphorbiaceae) leaf on anthropometric and haematological parameters in rats.

is a plant used in traditional medicine to treat many illnesses. Previous studies showed the efficacy of the aqueous extract of leaf of this plant (AEMb) in the treatment of gastric ulcer within the dose range of 125-500 mg/kg body weight (b.w.

Mass spectrometry-based detection and risk assessment of mycotoxin contamination of 'kankankan' used for roasted meat consumption in Abidjan, Côte d'Ivoire.

'Kankankan' is a popular spice powder used to season roasted meat in Côte d'Ivoire. However, produced in a traditional way, the conditions of production and storage of kankankan favour the proliferation of mycotoxin-producing fungal strains. The aim of this study was to carry out an inventory of mycotoxin contamination of this spice powder and to assess risk exposure to consumers.

Transcription factor NF-κB in a basal metazoan, the sponge, has conserved and unique sequences, activities, and regulation.

Herein, we characterize transcription factor NF-κB from the demosponge Amphimedon queenslandica (Aq). Aq-NF-κB is most similar to NF-κB p100/p105 among vertebrate proteins, with an N-terminal DNA-binding domain, a C-terminal Ankyrin (ANK) repeat domain, and a DNA binding-site profile akin to human NF-κB proteins. Like mammalian NF-κB p100, C-terminal truncation allows nuclear translocation of Aq-NF-κB and increases its transcriptional activation activity.