Publications by authors named "A E Weel"
Background: Musculoskeletal joint complaints (MSCs) are the most common extraintestinal manifestation of inflammatory bowel disease (IBD). We aimed to investigate the effect of MSC on the health-related quality of life (QoL) in patients with IBD.
Design: A survey-based cross-sectional study among adult Dutch IBD patients.
Article Synopsis
- The study aimed to create a framework based on value-based healthcare principles to assess health outcomes and costs on an institutional level, specifically investigating how these factors are related.
- Conducted as a retrospective cohort study at a teaching hospital in Rotterdam, the research involved two populations: bariatric patients (856 total) and breast cancer patients (663 total), analyzing their health outcomes and associated costs of care.
- Results indicated high quality cost indicators (QCI) for both populations, with the bariatric group maintaining stable costs and the breast cancer group showing more variability, while poor health outcomes were linked to increased hospital costs in both groups.
Objective: To assess the cost-utility from healthcare and societal perspectives of the digital CaFaSpA referral strategy (CS) for axial spondyloarthritis (axSpA) in primary care patients with chronic low back pain (CLBP).
Method: A cluster randomized controlled trial was performed in the Netherlands. General practice units were randomized into CS or usual care (UC).
Increase in axial spondyloarthritis diagnoses after the introduction of the ASAS criteria: a systematic review.
Rheumatol Int
April 2023
To explore the proportion of axial spondyloarthritis (axSpA) and psoriatic arthritis (PsA) diagnoses within all newly referred patients visiting rheumatology outpatient clinics. And more specifically, to analyze whether there is an effect of the introduction of the ASAS and CASPAR classification criteria for axSpA and PsA. We systematically searched Embase, Medline Ovid, Cochrane Central and Web of Science from database inception to November 2022.
View Article and Find Full Text PDF[Is bone marrow edema a cause of low back pain? A possible role of bacteria].
Ned Tijdschr Geneeskd
February 2022
Lumbar bone marrow edema, also known as Modic type-1 endplate change, has a prevalence of 43% in low back pain populations and 6% in general populations. Besides mechanical factors and genetic predisposition it has been hypothesized that lumbar bone marrow edema is caused by a latent infection of low-virulence anaerobic bacteria in degenerated lumbar intervertebral discs. The hypothesis is supported by the observation that the presence of Cutibacterium acnes is more frequently found in samples of disci with Modic-1 than in discs without and by the positive effects of antibiotics in patients with back pain and Modic-1 as shown in placebo-controlled RCT's.
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