Publications by authors named "A E Spooner"

The healthcare landscape has long been characterized by a noticeable separation between the medical and dental fields, influencing how both oral and overall health are perceived and managed today. Long ago, tooth extraction was perceived as a form of entertainment, with barber-surgeons conducting procedures in front of crowds.1 Dentistry's transformation into a profession in the mid-1800s established a separate educational path, intensifying the divergence between medical and dental healthcare.

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  • Lymphoma is a significant cancer in Australia, and there is limited research on post-treatment care for survivors, highlighting the need for effective survivorship interventions.
  • This study evaluated the feasibility and acceptability of a nurse-led intervention called ENGAGE for lymphoma survivors, comparing it to an education-only group and usual care.
  • Results showed that ENGAGE was well-received, with high completion rates and participant satisfaction, suggesting it could be a promising option for supporting lymphoma survivors in a larger future study.
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  • The study analyzes the midterm clinical outcomes of robotic-assisted reverse hybrid coronary revascularization (HCR) in 285 patients over a period from 2005 to 2021.
  • The procedure involved stent implantation prior to robotic-assisted harvesting of the left internal thoracic artery, followed by anastomosis without any conversions to full sternotomy.
  • Results showed a low incidence of complications post-surgery, with midterm follow-up indicating a 10.9% all-cause mortality rate and 35.9% experiencing major cardiovascular events, suggesting that reverse HCR is safe and effective for multivessel coronary artery disease.
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This reflection paper presents a consolidated view of EFPIA on the need for principles for good practice in the generation and use of non-interventional studies (NIS), including overarching principles such as the registration of hypothesis evaluating treatment effect (HETE) studies. We first define NIS and the important adjacencies to clinical trials and relationship with real-world evidence (RWE). We then outline the principles for good practice with respect to appropriate research design, study protocol, fit-for-purpose variables and data quality, analytical methods, bias reduction, transparency in conduct and use, privacy management and ethics review.

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