Publications by authors named "A E Pereverzev"
This study presents a mechanism of ammonia oxidation catalyzed by [Ru(NH)][PF] (Ru=Ru(tpy)(dmabpy)) complexes. All intermediates, including the elusive [Ru(NH)] and [Ru(NH)], were detected, with several intermediates characterized spectroscopically. The catalytic cycle follows multiple reaction pathways branching at the key intermediates [Ru(NH)] and [Ru(NH)].
View Article and Find Full Text PDFThe discovery of new transformations drives the development of synthetic organic chemistry. While the main goal of synthetic chemists is to obtain the maximum yield of a desired product with minimal side product formation, meticulous characterization of the latter offers an opportunity for discovering new reaction pathways, alternative mechanisms, and new products. Herein, we present a case study on the discovery and development of a new chemical transformation using online mass spectrometry.
View Article and Find Full Text PDFTraumatic brain injury alters the effects of class II invariant peptide (CLIP) antagonism on chronic meningeal CLIP + B cells, neuropathology, and neurobehavioral impairment in 5xFAD mice.
J Neuroinflammation
June 2024
Article Synopsis
- - The study investigates the impact of a CLIP antagonist peptide (CAP) on B cell expansion and neuroprotective effects in 5xFAD mice, which are a model for Alzheimer's disease and have a history of traumatic brain injury (TBI).
- - Results showed that treatment with CAP significantly reduced CLIP-positive B cells and improved various impairments related to the immune system and neurobehavioral functions in the 5xFAD mice over a period of six months.
- - However, TBI seemed to negate the effectiveness of CAP in reducing B cell populations and also exacerbated several pathological features of Alzheimer's disease, indicating a complex interaction between TBI and AD.
Article Synopsis
- Electrochemical methods are gaining popularity in green chemistry due to their potential for sustainability.
- Understanding reactions at the electrode-solution interface is key, and the study uses a combination of techniques, including voltammetry and mass spectrometry, for real-time monitoring.
- The research reveals important insights into the electrocatalytic processes involved in the reduction of oxygen, showing reaction intermediates and degradation pathways, which could improve optimization in sustainable electrochemical reactions.
The premise of most studies on the homogeneous electrocatalytic CO reduction reaction (CORR) is a good understanding of the reaction mechanisms. Yet, analyzing the reaction intermediates formed at the working electrode is challenging and not always attainable. Here, we present a new, general approach to studying the reaction intermediates applied for CORR catalyzed by a series of cobalt complexes.
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