Publications by authors named "A E Martirosyan"
Antiphospholipid syndrome (APS) is associated with recurrent pregnancy morbidity, yet the underlying mechanisms remain elusive. We performed multifaceted characterization of the biological and transcriptomic signatures of mouse placenta and uterine natural killer (uNK) cells in APS. Histological analysis of APS placentas unveiled placental abnormalities, including disturbed angiogenesis, occasional necrotic areas, fibrin deposition, and nucleated red blood cell enrichment.
View Article and Find Full Text PDF[Long-term outcomes of minimally invasive coronary artery bypass grafting].
Khirurgiia (Mosk)
December 2024
Article Synopsis
- The study compared long-term outcomes of minimally invasive coronary artery bypass grafting (MICS CABG) with traditional surgery through sternotomy, involving 158 patients for MICS and 150 for sternotomy.
- The results showed no significant differences in 5-year survival rates or freedom from adverse cardiac events between the two groups, but MICS CABG had lower rates of wound complications and shorter hospital stays.
- Overall, MICS CABG proved to be a safe and effective alternative, offering similar long-term results while providing benefits like faster recovery and reduced rehabilitation time, particularly for patients at higher risk of complications.
Purpose: To investigate structural alterations in the thalamus in patients with primary trigeminal neuralgia and provide a detailed perspective on thalamic remodeling in response to chronic pain at the level of individual thalamic nuclei. METHODS: We analyzed a sample of 62 patients with primary trigeminal neuralgia who underwent surgical treatment, along with 28 healthy participants. Magnetic resonance imaging (MRI) data were acquired using a 3T system equipped with a 16-channel receiver head coil.
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- Moyamoya disease is a rare brain condition that increases the risk of strokes, which can be life-threatening.
- Over a 4-year period, a patient was closely monitored after developing symptoms and undergoing two successful revascularization surgeries.
- The study's findings suggest that while these surgeries help prevent future strokes, they result in only slight improvements in cognitive function.
Traumatic brain injury (TBI) can result in long-lasting changes in hippocampal function. The changes induced by TBI on the hippocampus contribute to cognitive deficits. The adult hippocampus harbors neural stem cells (NSCs) that generate neurons (neurogenesis), and astrocytes (astrogliogenesis).
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