Zh Nevrol Psikhiatr Im S S Korsakova
January 2013
Concentrations of plasma vascular tone regulation markers that are indicators of endothelium dysfunction in the acute phase of ischemic stroke and their effect on the development of hemorrhagic transformation (HT) of the lesion focus have been studied. Concentrations of renin, endothelin 1-21, neuron-specific enolase, NT-proCNP, soluble adhesion molecules (sICAM) were measured in 67 patients on days 1, 3-4. Significantly higher concentrations of renin, endothelin 1-21, neuron-specific enolase were found in patients with HT in the first day compared to patients without HT.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2010
Passive tilt table test is one of the methods of early rehabilitation in the most acute and acute periods of stroke. We included 36 patients with stroke: 17 patients underwent passive tilting using "Lojer 1445YH" (a main group), 19 patients underwent changing position with a functional bed (a control group) on days 1, 2, 3, 5, 7, 14 and 21 after the onset of disease. Some patients were intolerant to passive tilting due to decreasing of systolic blood pressure to more than 20 mm Hg in the first 48 h after stroke.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
December 2010
Today the systemic thrombolytic therapy with recombinant tissue plasminogen activator (rt-PA) is the most effective treatment of ischemic stroke. We included 116 patients with stroke, 82 received rt-PA, 34 were enrolled to the control group. Median NIHSS score was 16,2 +/- 5,4 in the main group and 16,2 +/- 5,4 in the control group.
View Article and Find Full Text PDFZh Nevrol Psikhiatr Im S S Korsakova
July 2011
Recent studies showed that the increase of fibrinogen preceded not only thrombolytic events but also the development of intracerebral hemorrhage. The objective of the present study was to determine the threshold levels of fibrinogen concentration for the prognosis of ischemic stroke complications and, particularly, hemorrhagic transformation. Fibrinogen concentrations in patients with acute cerebral hemispheric stroke without thrombolytic treatment were examined.
View Article and Find Full Text PDFThe positions of patients and medical personnel are described in this article. The problems of prevention in elders and medical education of patients are investigated.
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