Publications by authors named "A E Krill"
Introduction: Hydronephrosis grading systems risk stratify patients with potential ureteropelvic junction obstruction, but only some criteria are measured objectively. Most notably, there is no consensus definition of renal parenchymal thinning.
Objectives: The objective of this study was to assess the association between sonographic measures of renal length, renal pelvic diameter, and renal parenchymal thickness and the outcomes of a)renal hypofunction(differential renal function{DRF} <40%) and b)high-risk renal drainage(T1/2 > 40 min).
Article Synopsis
- This study examines hydronephrosis in the lower part of duplex kidneys, using a technique called MAG-3 diuresis renography to assess its prevalence and behavior compared to single-system kidney obstructions.* -
- Researchers analyzed over 5000 diuresis renograms and identified 19 affected renal units in 18 patients, noting that many cases were diagnosed before birth and showed varied drainage patterns during follow-up.* -
- The findings suggest that hydronephrosis in duplex systems is uncommon but similar in behavior to obstructions in single kidneys, highlighting the importance of diuresis renography in diagnosis and treatment.*
Background: In times of genotype guided therapy options, a total of 3.2 % of people with CF (pwCF) in the German CF Registry[1] only have one or no CFTR-variant detected after genetic analysis. Additionally, genetic data in the Registry can be documented as free text and can therefore be prone to error.
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- Hydronephrosis from UPJ obstruction is common in infants with prenatal diagnosis, leading to surgeries like pyeloplasty due to drainage issues or kidney function decline, but the natural history of cases with non-obstructive drainage and reduced renal function is not well understood.
- The study analyzed data from patients with significant hydronephrosis and low differential renal function, observing them over time to determine how many experienced worsening kidney drainage or function decline.
- Out of 29 patients studied over an average of 2.8 years, nearly half showed worsening drainage, with some requiring surgery, while a few managed to improve without obstructive patterns.
Introduction And Objective: Prior studies have shown a broad half time (T1/2) interval on MAG3 diuresis renography (DR) that is indeterminate for obstruction. We aimed to refine and sub-divide the indeterminate range and associate it with clinically meaningful outcomes: pyeloplasty and pyeloplasty-free survival.
Methods: We identified patients <1.