Directed Evolution of Silicatein Reveals Biomineralization Synergism between Protein Sequences.

Biomineralization is a green synthesis route for a variety of metal nanoparticles. Silicatein is a biomineralization protein originally found in marine sponge that converts inorganic precursors to metal oxide nanoparticles. In this work, we investigate the popular catalytic triad hypothesis and implement directed evolution with the aim to improve the solubility and kinetics of silicatein to enable increased nanoparticle synthesis.

Neighborhood collective efficacy reduces child maltreatment through decreasing parenting stress: A longitudinal path model.

Background: Neighborhoods and families are crucial contexts for child maltreatment, yet research into mechanisms of neighborhood effects on child maltreatment remains limited.

Objective: This study examined longitudinal associations between neighborhood collective efficacy, maternal parenting stress, and child maltreatment.

Participants And Setting: The study drew data from the Future of Families and Child Wellbeing Study (FFCWS).

Organizational strategies of eldercare work and health - Is the daily number of residents cared for over 14 months associated with back pain?

Objectives: The growing care demands of an aging population and a smaller workforce is a big societal problem. Therefore, knowledge on how to organize eldercare work without hampering workers` health is needed. We aimed to investigate if workers` daily number of residents cared for over 14 months is associated with low-back pain in eldercare workers.

In-Cage Recombination Facilitates the Enantioselective Organocatalytic [1,2]-Rearrangement of Allylic Ammonium Ylides.

The [1,2]-rearrangement of allylic ammonium ylides is traditionally observed as a competitive minor pathway alongside the thermally allowed [2,3]-sigmatropic rearrangement. Concerted [1,2]-rearrangements are formally forbidden, with these processes believed to proceed through homolytic C-N bond fission of the ylide, followed by radical-radical recombination. The challenges associated with developing a catalytic enantioselective [1,2]-rearrangement of allylic ammonium ylides therefore lie in biasing the reaction pathway to favor the [1,2]-reaction product, alongside controlling a stereoselective radical-radical recombination event.

Maternal self-efficacy during infancy: Investigating the roles of depression and social support among mothers in rural Pakistan.

Maternal self-efficacy during infancy is shaped by many factors, including maternal mental health and social support. This study examines how depression, emotional support, and childcare support relate to maternal self-efficacy among mothers of infants in rural Pakistan. Participants included 885 mothers assessed at 3 and 6 months postpartum.