MOHS Patients Can Reliably Estimate Preoperative Non-Melanoma Skin Cancer Size.

As the presurgical size and anatomic location of non-melanoma skin cancer correlates to the complexity of Mohs micrographic surgery (MMS), patients are frequently asked to self-report their preoperative tumor size to aid in efficient scheduling and triage. We aimed to assess the accuracy of patient's self-reported lesion measurements prior to MMS by comparing patient's estimates of lesion size to the measurements taken by a Mohs surgeon. We conducted a retrospective chart review of 1,000 patients who underwent MMS and self-reported their lesion size at a preoperative telehealth visit.

Race and appointment availability influence continuity of care for chronic inflammatory skin disease: A cross-sectional study of United States practice data.

Background: In the management of chronic inflammatory skin disease (CISD), continuity of care may influence the achievement of long-term disease control. Barriers to care have been identified in this population, which may leave some patients more vulnerable to loss of follow-up.

Objective: We aim to identify predictors of continuity of care for CISD patients across demographic groups and health care practice types in the United States.

Dermatologist Characteristics Associated With Outlier Performance of Destruction for Benign Lesions.

Background: Destruction of a benign skin lesion should not be billed to Medicare if the lesion is solely a cosmetic concern. Reducing unnecessary benign destructions could lower Medicare costs.

Objective: Evaluate benign destruction rates relative to premalignant destruction rates and identify factors associated with frequent benign destruction among dermatologists.

Advanced Practice Providers and Western Providers Are Associated With Increased Likelihood of Benign Skin Biopsies: A Cross-sectional Analysis.

Background And Objective: To identify provider-related characteristics associated with a higher proportion of benign skin biopsies.

Patients And Materials/methods: Medicare Part B database was analyzed, and for each provider, the number of skin biopsies that he/she performed that were benign lesions was estimated.

Results: Increased benign skin biopsies were performed by nurse practitioners and physician assistants (as compared to Doctor of Medicine/Doctor of Osteopathic Medicine) (odds ratio [OR] of 1.

The novel estrogen receptor beta agonist EGX358 and genotype influence memory, vasomotor, and anxiety outcomes in an Alzheimer's mouse model.

Introduction: Alzheimer's disease (AD) prevalence and severity are associated with increased age, female sex, and apolipoprotein E4 (APOE4) genotype. Although estrogen therapy (ET) effectively reduces symptoms of menopause including hot flashes and anxiety, and can reduce dementia risk, it is associated with increased risks of breast and uterine cancer due to estrogen receptor alpha (ERα)-mediated increases in cancer cell proliferation. Because ERβ activation reduces this cell proliferation, selective targeting of ERβ may provide a safer method of improving memory and reducing hot flashes in menopausal women, including those with AD.