[Clarythromycin in the treatment of exacerbations of chronic obstructive lung disease].

Clarythromycin (Clerimed) is an antibiotic that has a high antibacterial potential, is successfully used in the treatment of moderate and severe exacerbations of Stage II chronic obstructive lung disease (COLD). Comparison of the clinical efficacy of Clerimed with beta-lactams and respiratory fluoroquinolones has indicated the equal clinical efficacy of the compared groups of drugs. A functional and laboratory monitoring of patients with an exacerbation of COLD treated with Clerimed has established that the most pronounced changes (improvement) occur within the first week of antibiotic therapy, which is typical of control patients.

[Myocardial contraction and intensive therapy in phthisiosurgical patients].

The changes in myocardial contractility were studied in 88 patients operated on for pulmonary tuberculosis in pre- and postoperative periods using echocardiography. It was found that among patients operated on for acute and common forms of pulmonary tuberculosis tahere was a considerable proportion of those with hypo- and hyperkinetic types of central hemodynamics which were characterized by unstable hemodynamic parameters and needed corrective therapy both in pre- and postoperative periods. Strategy of preoperative preparation and postoperative management of patients was elaborated by the status of the central hemodynamics.