Publications by authors named "A E Clague"

Adverse childhood events (ACE) may have lasting consequences throughout the life course. We focus on one particular type of ACE, parental loss in Cambodia-a country that lost nearly 25% of its population during the 1975-79 Khmer-Rouge regime-and on mental health disorders, one of the potential mechanisms through which ACE may have long-term consequences. Self-reports of symptoms that map on to the Diagnostic and Statistical Manual of Mental Health Disorders (DSM) criteria for anxiety, depression, and post-traumatic stress disorder (PTSD) were collected from 4,405 adults aged 20 and over.

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The U.S. Air Force asked RAND Project AIR FORCE (PAF) to help assess the well-being of its wounded members and the quality of services provided to facilitate their recovery and reintegration.

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Background And Aims: Although malnutrition is common in liver disease, there are limited data on fat soluble vitamins in various diseases. The aims of this study were to: (i) determine fat soluble vitamin levels in patients assessed for liver transplantation; (ii) compare levels between different disease etiologies (hepatocellular and cholestatic) and between subgroups of hepatocellular disease; and (iii) assess the multivariate contribution to vitamin levels of etiology and various indicators of disease severity.

Methods: This was a cross-sectional study of 107 inpatients awaiting liver transplantation, mean age 47 years.

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Background/aims: Although vitamin A deficiency is common in chronic liver disease, limited data exist on impairment of dark adaptation and response to therapy. The aims were (1) to assess dark adaptation in patients, (2) to assess the relationship between dark adaptation and vitamin A status, zinc and Child-Pugh score, (3) to compare perceived and measured dark adaptation and (4) to assess the dark adaptation response to intramuscular vitamin A.

Methods: This was a prospective study of 20 patients (alcoholic liver disease 10, other parenchymal diseases six, cholestatic diseases four) awaiting liver transplantation.

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Aim: To evaluate the correlation between raised soluble transferrin receptor (sTfR) and stainable marrow iron, and to define the utility of sTfR in discriminating between the presence or absence of iron-deficient erythropoiesis in patients with anaemia of chronic disease.

Methods: Seventy-six consecutive adult patients without accelerated erythropoiesis who had undergone bone marrow (BM) aspiration/trephine for various clinical reasons during 2003-2006 were studied. All patients had serum iron studies (iron, transferrin and ferritin) and sTfR performed within 1 week of BM aspiration/trephine.

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