Publications by authors named "A E Calogero"
Objective: Preclinical evidence has demonstrated that gut microbiota composition can influence steroid hormone biosynthesis and spermatogenesis. This study aims to investigate the association of seminal microbiota and testicular steroidogenesis.
Patients And Methods: One hundred adult eugonadal men were consecutively enrolled.
Introduction: The risk of HCC is twice as high in diabetic patients compared to non-diabetic ones, suggesting that diabetes advances carcinogenesis in the liver through a variety of mechanisms. Sodium-glucose cotransporter 2 inhibitors (SGLT2i) have been shown to improve liver outcomes, emerging as promising agents to treat hepatocellular carcinoma (HCC) in patients with type 2 diabetes mellitus (T2DM).
Methods: We searched PubMed and Scopus databases for articles presenting an association between SGLT2is and HCC to explore the putative mechanisms of action underlying the anti-proliferative activity of SGLT2is.
Article Synopsis
- Varicocele affects up to 15% of men and is linked to infertility; various surgical and radiological methods exist for treatment, but their effectiveness is uncertain.
- A study comparing the Ivanissevich surgical technique and sclerotherapy in 94 patients found that sclerotherapy significantly improved sperm concentration, while surgical treatment reduced the number of patients with oligozoospermia.
- Overall, the study did not determine a clear advantage of one method over the other but highlighted the importance of considering sperm bio-functional parameters in future research.
α-synuclein oligomers within synaptic terminals of autonomic fibers of the skin reliably discriminate Parkinson's disease (PD) patients from healthy controls. Nonetheless, the prognostic role of oligomers for disease progression is unknown. We explored whether α-synuclein oligomers evaluated as proximity ligation assay (PLA) score may predict the worsening of cognitive functions in patients with Parkinson's disease.
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