[Experience in using hydrotherapy in children with acute lymphoblastic leukemia at a sanatorium].

34 children aged 10-15 years in long-term remission of acute lymphoblastic leukemia were on combined rehabilitation for concomitant diseases. Adjuvant balneotherapy promoted improvement in the heart rate and decreased asymmetry of circulation. No side effects were registered.

[Use of intra-arterial chemotherapy in the treatment of malignant tumors in children].

Transcatheter arterial chemotherapy has been perfected in the treatment of 66 patients with various severe malignant tumors. A total of 75 arterial cytostatic injections were made, out of them 57 were given in primary tumors and 18 in tumor metastases. The children's age ranged from 1 to 14 years.

[The rate of antipyrine metabolism in cancer patients administered specific therapy].

Liver monooxygenase (MO) activity was evaluated in 31 children with oncological diseases. The enzyme activity was assessed by measuring the saliva half life of the test drug antipyrine. It was shown that MO activity is reduced in hepatitis, metastatic lesions of the liver, after long-term chemotherapy, combined treatment or progress of disease.

[The role of the day hospital in providing diagnostic and therapeutic care for children with malignant tumors].

The day hospital proved effective for diagnosis and treatment of pediatric cancer. It is more cost-effective and less emotionally traumatic for patients than the usual hospital.

[Evolution of drug treatment of rhabdomyosarcoma in children].

Rhabdomyosarcoma is the most frequently occurring type of malignant solid tumors in children. The tumor site, aggressive growth, proneness to recurrence, metastatic spreading, and high neglect predetermine the negligible share of the surgical method in multimodality treatment of rhabdomyosarcomas. Of importance are the development and the use of different types and schemes of drug therapy which can be employed in combination with radiotherapy.