Publications by authors named "A E Brooke"

Objective: Resuscitative endovascular balloon occlusion of the aorta (REBOA) is designed to manage severe hemorrhagic shock. Popularized in medical care during military conflicts, the concept has emerged as a lifesaving technique that is utilized around the United States. Literature on risks of REBOA placement, especially vascular injuries, are not well-reported.

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  • * The synthesized carbon structures were designed to have a uniform pore structure, enhancing electrochemical properties and increasing the detection of dopamine and other neurochemicals.
  • * This research highlights the potential of using biowastes for advanced biosensing applications, demonstrating that the design of surface nanostructures significantly impacts electrochemical detection capabilities.
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Plastic waste is a critical global issue, yet current strategies to avoid committing plastic waste to landfills include incineration, gasification, or pyrolysis high carbon emitting and energy consuming approaches. However, plastic waste can become a resource instead of a problem if high value products, such as fine chemicals and liquid fuel molecules, can be liberated from controlled its decomposition. This letter presents proof of concept on a low-cost, low energy approach to controlled decomposition of plastic, photocatalytic hydrolysis.

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The communication between the nervous and immune systems plays a crucial role in regulating immune cell function and inflammatory responses. Sympathetic neurons, which innervate the spleen, have been implicated in modulating immune cell activity. The neurotransmitter norepinephrine (NE), released by sympathetic neurons, influences immune cell responses by binding to adrenergic receptors on their surface.

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  • The study aims to improve the understanding of non-functioning pituitary microadenomas (micro-NFPAs) and their natural progression to inform patient care.
  • Conducted across 23 endocrine departments in the UK, it analyzed clinical data from 459 patients over a median of 3.5 years, assessing tumor growth and hormonal changes.
  • Results indicate a low probability of tumor growth (7.8% at 3 years) and rare development of hypopituitarism, suggesting that follow-up MRIs every 3 years and less frequent hormonal checks are adequate for managing micro-NFPAs.
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