Antibody-based research applications are critical for biological discovery. Yet there are no industry standards for comparing the performance of antibodies in various applications. We describe a knockout cell line-based antibody characterization platform, developed and approved jointly by industry and academic researchers, that enables the systematic comparison of antibody performance in western blot, immunoprecipitation and immunofluorescence.
View Article and Find Full Text PDFData interoperability is crucial for effectively combining data for scientific inquiry. To facilitate interoperability, data standards such as a common definition of variables are often developed. The Open Data Commons for Spinal Cord Injury (odc-sci.
View Article and Find Full Text PDFTables are useful information artifacts that allow easy detection of data "missingness" by humans and have been deployed by several publishers to improve the amount of information present for key resources and reagents such as antibodies, cell lines, and other tools that constitute the inputs to a study. The STAR*Methods tables, specifically, have increased the "findability" of these key resources, but they have not been commonly available outside of the Cell Press journal family. To improve the availability of these tables in the broader biomedical literature, we have attempted to automatically process BioRxiv preprints to create tables from text or to recognize tables already created by authors and structure them for later use by publishers and search systems, to improve "findability" of resources in a larger amount of the scientific literature.
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