Publications by authors named "A E Bandrowski"

Antibody-based research applications are critical for biological discovery. Yet there are no industry standards for comparing the performance of antibodies in various applications. We describe a knockout cell line-based antibody characterization platform, developed and approved jointly by industry and academic researchers, that enables the systematic comparison of antibody performance in western blot, immunoprecipitation and immunofluorescence.

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Data interoperability is crucial for effectively combining data for scientific inquiry. To facilitate interoperability, data standards such as a common definition of variables are often developed. The Open Data Commons for Spinal Cord Injury (odc-sci.

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Tables are useful information artifacts that allow easy detection of data "missingness" by humans and have been deployed by several publishers to improve the amount of information present for key resources and reagents such as antibodies, cell lines, and other tools that constitute the inputs to a study. The STAR*Methods tables, specifically, have increased the "findability" of these key resources, but they have not been commonly available outside of the Cell Press journal family. To improve the availability of these tables in the broader biomedical literature, we have attempted to automatically process BioRxiv preprints to create tables from text or to recognize tables already created by authors and structure them for later use by publishers and search systems, to improve "findability" of resources in a larger amount of the scientific literature.

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Article Synopsis
  • Antibodies are important in scientific research, but many of them haven't been properly tested, making some research results questionable.
  • There have been efforts to fix this problem, especially for antibodies that work with human proteins.
  • The article suggests ways that different people and organizations, like researchers and universities, can help make sure future studies with antibodies are more reliable.
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Article Synopsis
  • The use of living biological samples is crucial for preserving and documenting biological diversity, requiring reliable identification and data association for effective use and exchange of these materials.
  • There is currently no standardized naming system for identifying animal biological materials, which can lead to misidentification and data loss.
  • A newly proposed naming scheme aims to create unique identifiers for animal cellular materials, particularly for wildlife species, enhancing traceability and supporting long-term conservation efforts and biomedical research.
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