Publications by authors named "A E Athanasiou"
Article Synopsis
- Early detection of pancreatic ductal adenocarcinoma (PDAC) is crucial for improving survival, but current methods like imaging and the CA19-9 blood test lack sensitivity for early-stage tumors.
- A study was conducted to identify a blood-based protein signature that performs better than CA19-9, analyzing approximately 3000 proteins and using machine learning to create multiple biomarker signatures.
- The new signatures showed significant improvements, achieving 84% sensitivity at 95% specificity, compared to CA19-9’s 53% sensitivity, and identified 41 promising biomarker candidates for further validation.
Palatal rugae change shape following orthodontic treatment: a comparison between extraction and non-extraction borderline cases using fractal analysis and 3D superimposition.
Eur J Orthod
December 2024
Article Synopsis
- This study focuses on the changes in palatal rugae (the ridges on the hard palate) following orthodontic treatment, investigating whether their shape, complexity, and area are affected by treatment with or without tooth extractions.
- Researchers analyzed pre- and post-treatment plaster models from a sample of 61 cases, using advanced software to measure changes in the outlines, fractal dimensions (complexity), and area occupied by the rugae.
- Results showed significant differences in the distance between pre- and post-treatment outlines for extraction versus non-extraction groups, but no significant changes in the complexity of the rugae before and after treatment.
Importance: Breast cancer is one of the leading causes of negligence claims in radiology. The objective of this document is to describe the specific main causes of errors in breast imaging and provide European Society of Breast Imaging (EUSOBI) recommendations to try to minimize these.
Observations: Technical failures represent 17% of all mammographic diagnostic negligence claims.
Importance: Misdiagnosis in breast imaging can have significant implications for patients, healthcare providers, and the healthcare system as a whole.
Observations: Some of the potential implications of misdiagnosis in breast imaging include delayed diagnosis or false reassurance, which can result in a delay in treatment and potentially a worse prognosis. Misdiagnosis can also lead to unnecessary procedures, which can cause physical discomfort, anxiety, and emotional distress for patients, as well as increased healthcare costs.
Article Synopsis
- Adenomyosis is a painful condition affecting women that can lead to symptoms like severe menstrual pain, heavy bleeding, and infertility, and new thermal ablation techniques present minimally invasive treatment options.
- Techniques like high-intensity focused ultrasound, microwave ablation, and radiofrequency ablation are found to effectively reduce symptoms and uterine size without compromising fertility or requiring lengthy hospital stays.
- Despite promising results regarding safety and effectiveness, further research is needed to compare these new treatments to traditional therapies to inform future medical decisions.